Characterizing Drug–Target Interactions: Shifting towards the Clinic: Trends in Pharmacological Sciences
Translational drug discovery and development with the use of tissue‐relevant biomarkers: Towards more physiological relevance and better prediction of clinical efficacy - Florian - 2020 - Experimental Dermatology - Wiley Online Library
Promega NanoLuc Enables a First in Measuring Drug-Target Residence in Live Cells | Business Wire
NanoBRET Target Engagement | Live-Cell Compound Binding Assay
Promega Launches NanoBRET™ Target Engagement Intracellular Kinase Assay, First to Quantitatively Measure Drug-Kinase Interactions in Live Cells | Business Wire
Nerd Bio - Drug Discovery, Undruggable, Lead Discovery, Drug Target
InCELL Target Engagement Assays -
Screening for Target Engagement using the Cellular Thermal Shift Assay - CETSA - Assay Guidance Manual - NCBI Bookshelf
Labelled chemical probes for demonstrating direct target engagement in living systems | Future Medicinal Chemistry
Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery | PNAS
Determining target engagement in living systems | Nature Chemical Biology
Importance of Quantifying Drug-Target Engagement in Cells | ACS Medicinal Chemistry Letters
Ontotext's AI Powered Target Discovery
InCELL Target Engagement Assays -
Quantitative Kinase Target Engagement
Target Engagement Measures in Preclinical Drug Discovery: Theory, Methods, and Case Studies | SpringerLink
JCI - Taxane resistance in prostate cancer is mediated by decreased drug-target engagement
Target Engagement in Lead Generation - ScienceDirect
Antibody Drug-Target Engagement Measurement in Tissue Using Quantitative Affinity Extraction Liquid Chromatography–Mass Spectrometry: Method Development and Qualification | Analytical Chemistry
Reducing the Cost of Drug Development While Increasing Biological Understanding
Target Engagement for Drug Discovery
DNA-Encoded Libraries (DELs) and NanoBRET™ Target Engagement Assays Accelerate Drug Discovery
Quantitating drug-target engagement in single cells in vitro and in vivo | Nature Chemical Biology
